Jun-Ping Liu Selected Research

Telomerase (Telomerase Reverse Transcriptase)

1/2022	Molecular Mechanisms of Alveolar Epithelial Stem Cell Senescence and Senescence-Associated Differentiation Disorders in Pulmonary Fibrosis.
10/2021	Pulmonary Alveolar Stem Cell Senescence, Apoptosis, and Differentiation by p53-Dependent and -Independent Mechanisms in Telomerase-Deficient Mice.
1/2021	Pulmonary alveolar stem cells undergo senescence, apoptosis and differentiation by p53-dependent and -independent mechanisms in telomerase deficient mice.
1/2020	Role of telomerase in the tumour microenvironment.
1/2020	Molecular insight into the selective binding between human telomere G-quadruplex and a negatively charged stabilizer.
1/2017	Effects of the central potassium ions on the G-quadruplex and stabilizer binding.
1/2017	TGF-beta receptor mediated telomerase inhibition, telomere shortening and breast cancer cell senescence.
10/2016	hTERT promotes tumor angiogenesis by activating VEGF via interactions with the Sp1 transcription factor.
12/2015	Telomerase Deficiency Causes Alveolar Stem Cell Senescence-associated Low-grade Inflammation in Lungs.
9/2015	Characterization of potassium binding with human telomeres.

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Jun-Ping Liu Research Topics

Disease

40	Neoplasms (Cancer) 01/2021 - 08/2005
10	Breast Neoplasms (Breast Cancer) 01/2017 - 05/2002
6	Inflammation (Inflammations) 01/2022 - 01/2010
5	Carcinogenesis 01/2018 - 01/2002
5	Uterine Cervical Neoplasms (Cancer of the Cervix) 03/2016 - 11/2008
4	Fibrosis (Cirrhosis) 01/2022 - 10/2020
4	Neoplasm Metastasis (Metastasis) 01/2021 - 06/2013
2	Idiopathic Pulmonary Fibrosis 01/2022 - 10/2021
2	Colonic Neoplasms (Colon Cancer) 03/2016 - 12/2015
2	Leukemia 02/2015 - 08/2010
2	Chronic Hepatitis C 09/2013 - 04/2013
2	Nasopharyngeal Carcinoma 07/2011 - 10/2006
2	Disease Susceptibility (Diathesis) 05/2010 - 09/2009
2	Type C Niemann-Pick Disease (Niemann Pick Disease, Type C) 01/2010 - 01/2010
2	Atherosclerosis 09/2006 - 01/2002
1	Pulmonary Fibrosis (Fibrosing Alveolitis) 01/2022
1	Insulin Resistance 06/2021
1	Weight Loss (Weight Reduction) 06/2021
1	Hyperphagia (Overeating) 06/2021
1	Dementia (Dementias) 01/2021
1	Starvation 01/2021
1	COVID-19 11/2020
1	Hemorrhage 10/2020
1	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 10/2020
1	Squamous Cell Carcinoma of Head and Neck 01/2020
1	Hypoxia (Hypoxemia) 01/2020
1	B-Cell Lymphoma (Lymphoma, B Cell) 01/2018
1	Neuroblastoma 01/2018
1	Parkinsonian Disorders (Parkinsonism) 01/2017
1	Fever (Fevers) 09/2016
1	Communicable Diseases (Infectious Diseases) 09/2016
1	Vascular Diseases (Vascular Disease) 09/2016
1	Glioblastoma (Glioblastoma Multiforme) 03/2016
1	Prostatic Neoplasms (Prostate Cancer) 03/2016
1	Premature Aging 12/2015
1	Lung Diseases (Lung Disease) 12/2015
1	Muscular Diseases (Myopathy) 08/2014
1	Cardiac Arrhythmias (Arrythmia) 08/2014

Drug/Important Bio-Agent (IBA)

37	Telomerase (Telomerase Reverse Transcriptase)IBA 01/2022 - 01/2002
9	Proteins (Proteins, Gene)FDA Link 10/2020 - 01/2007
6	Pharmaceutical PreparationsIBA 01/2021 - 09/2009
5	DNA (Deoxyribonucleic Acid)IBA 01/2021 - 08/2008
5	Transforming Growth Factor beta (TGF-beta)IBA 05/2010 - 02/2006
5	EnzymesIBA 01/2010 - 10/2006
4	Peptides (Polypeptides)IBA 08/2020 - 01/2007
4	CytokinesIBA 01/2017 - 11/2008
3	telomerase RNA (bTR)IBA 01/2022 - 08/2012
3	Antiviral Agents (Antivirals)IBA 02/2015 - 04/2013
3	Transcription Factors (Transcription Factor)IBA 06/2013 - 08/2008
3	Estrogens (Estrogen)FDA Link 04/2011 - 09/2006
2	Blood Glucose (Blood Sugar)IBA 06/2021 - 05/2012
2	ChromatinIBA 01/2020 - 07/2014
2	Small Interfering RNA (siRNA)IBA 01/2018 - 06/2008
2	LipidsIBA 01/2017 - 01/2010
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 10/2016 - 06/2008
2	dactolisibIBA 03/2016 - 12/2015
2	CholesterolIBA 01/2010 - 01/2010
2	AntigensIBA 01/2010 - 01/2007
2	Neoplasm Antigens (Tumor Antigens)IBA 01/2010 - 01/2007
2	Phosphotransferases (Kinase)IBA 01/2007 - 11/2005
1	Tripeptidyl-Peptidase 1IBA 01/2022
1	SenotherapeuticsIBA 01/2022
1	Insulin ReceptorIBA 06/2021
1	Glucose (Dextrose)FDA LinkGeneric 06/2021
1	Oxidants (Oxidizing Agents)IBA 01/2021
1	Bleomycin (Blenoxane)FDA LinkGeneric 11/2020
1	Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA 11/2020
1	fibrin fragment D (D-dimer)IBA 10/2020
1	Anti-Infective Agents (Microbicides)IBA 08/2020
1	Chloroform (Trichloromethane)IBA 07/2020
1	histone deacetylase 3IBA 01/2020
1	bromodichloromethaneIBA 12/2019
1	Programmed Cell Death 1 ReceptorIBA 01/2019
1	LigandsIBA 01/2019
1	AntibodiesIBA 01/2019
1	Poly Adenosine Diphosphate RiboseIBA 01/2018
1	Caspase 8 (Caspase-8)IBA 01/2018
1	Caspase 9IBA 01/2018
1	Caspase 3 (Caspase-3)IBA 01/2018
1	Mitogen-Activated Protein KinasesIBA 01/2018
1	Nuclear Proteins (Protein, Nuclear)IBA 01/2018
1	Transforming Growth Factor beta Receptors (TGF beta Receptors)IBA 01/2017
1	Sp1 Transcription FactorIBA 10/2016
1	ProcalcitoninIBA 09/2016
1	CollagenIBA 09/2016
1	Ferritins (Ferritin)IBA 09/2016
1	icariinIBA 03/2016
1	PlatinumIBA 03/2016
1	furanIBA 03/2016
1	GSK343IBA 03/2016
1	Histone MethyltransferasesIBA 03/2016
1	Cholecalciferol (Vitamin D3)FDA Link 03/2016
1	Insulin (Novolin)FDA Link 12/2015
1	Toll-Like Receptors (Toll-Like Receptor)IBA 02/2015
1	Crystallins (Crystallin)IBA 08/2014

Therapy/Procedure

11	Therapeutics 01/2022 - 01/2007
3	Immunotherapy 01/2019 - 01/2007
2	Drug Therapy (Chemotherapy) 01/2010 - 01/2010
1	Splenectomy 10/2020
1	Sclerotherapy 10/2020